Guideline Atlas

Hemolytic anemia

Also known as: AIHA · autoimmune hemolytic anemia · G6PD deficiency · sickle cell disease

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United StatesASH/NCCN/ASCO
CurrentGlobal guideline

Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting

First International Consensus Group on Autoimmune Haemolytic Anaemia · 2020

An international expert consensus document on autoimmune haemolytic anaemia in adults, chosen as the representative guideline because no single US or EU society guideline is the recognised authority for this rare disease group. It sets out a standardised diagnostic work-up and treatment approach separately for warm antibody disease and cold agglutinin disease, and reviews emerging therapies.

  • Distinguishes warm-antibody autoimmune haemolytic anaemia from cold agglutinin disease because work-up, course and treatment differ. source
  • Treats the monospecific direct antiglobulin test as a required element of the diagnostic work-up. source
  • Published in Blood Reviews, volume 41, article 100648 (May 2020); the authorship spans European and North American centres. source
EuropeEHA/ESMO
CurrentGlobal guideline

Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting

First International Consensus Group on Autoimmune Haemolytic Anaemia · 2020

An international expert consensus document on autoimmune haemolytic anaemia in adults, chosen as the representative guideline because no single US or EU society guideline is the recognised authority for this rare disease group. It sets out a standardised diagnostic work-up and treatment approach separately for warm antibody disease and cold agglutinin disease, and reviews emerging therapies.

  • Distinguishes warm-antibody autoimmune haemolytic anaemia from cold agglutinin disease because work-up, course and treatment differ. source
  • Treats the monospecific direct antiglobulin test as a required element of the diagnostic work-up. source
  • Published in Blood Reviews, volume 41, article 100648 (May 2020); the authorship spans European and North American centres. source

US vs EU key differences

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