Lung cancer

Also known as: lung cancer screening · lung nodule · NSCLC · SCLC

Also relevant to Hematology & OncologyAlso relevant to Preventive Medicine & Primary Care

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United StatesATS/CHEST

Current

Management of Patients With Early-Stage Non-Small Cell Lung Cancer

CHEST (American College of Chest Physicians) · 2025

A CHEST guideline on primary treatment of stage I and II non-small cell lung cancer, published in 2025 with 17 evidence-based recommendations and decision algorithms stratified by operative risk.

Minimally invasive surgery is favoured over thoracotomy for clinical stage I disease. source
Lobectomy is preferred over sublobar resection for medically fit patients with centrally located or larger stage I tumours and for stage II disease. source

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EuropeERS (global: GOLD/GINA)

No ERS (global: GOLD/GINA) guideline indexed for this condition yet.

Every entry is added by hand and cited to the issuing society, so a gap here means we have not verified one — not that none exists. Know the right one? Tell us.

US vs EU key differences

No curated US/EU comparison yet for this disease.

What changed recently

US2013 → 20252025-07-01
Replacing the 2013 CHEST guideline on stage I and II NSCLC, the 2025 version backs minimally invasive resection over open thoracotomy on the strength of a new meta-analysis showing better overall survival, and accepts sublobar resection as equivalent to lobectomy for peripheral tumours of 2 cm or less. It also recommends adjuvant chemotherapy after complete resection of stage II disease and adjuvant targeted therapy for resected stage IB tumours carrying EGFR exon 19 deletion or L858R mutations.
source ↗curation confidence 90%

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