Sepsis & septic shock
Also known as: sepsis · septic shock · surviving sepsis
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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026
Surviving Sepsis Campaign (SCCM / ESICM) · 2026
An international, multi-society guideline on recognising and managing sepsis and septic shock in adults, covering hospital care as well as the immediately preceding prehospital and following post-hospital settings. It updates the 2021 edition with a substantially expanded set of statements.
- The 2026 edition contains 129 statements, of which 46 address topics not covered in earlier versions. source
- It keeps early recognition, timely treatment of infection and haemodynamic resuscitation as the organising pillars, and incorporates antimicrobial stewardship principles such as de-escalation. source
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026
Surviving Sepsis Campaign (SCCM / ESICM) · 2026
An international, multi-society guideline on recognising and managing sepsis and septic shock in adults, covering hospital care as well as the immediately preceding prehospital and following post-hospital settings. It updates the 2021 edition with a substantially expanded set of statements.
- The 2026 edition contains 129 statements, of which 46 address topics not covered in earlier versions. source
- It keeps early recognition, timely treatment of infection and haemodynamic resuscitation as the organising pillars, and incorporates antimicrobial stewardship principles such as de-escalation. source
US vs EU key differences
No curated US/EU comparison yet for this disease.
What changed recently
- GLOBAL2021 → 20262026-04-01
The 2026 edition expands to 129 statements, 46 of them on questions the 2021 guidelines never addressed, including a conditional recommendation for point-of-care ultrasound to guide resuscitation and new guidance on active fluid removal once initial resuscitation is complete. Of the 38 questions carried over from 2021, only three recommendations actually reversed direction.
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